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Research: Biochemical Reaction Shows How Acupuncture Works

Acupuncture Pain Killing Mystery Revealed

June 28, 2014

HealthCMI
Researchers have discovered that acupuncture causes a special biochemical reaction that reduces inflammation and muscle pain. The study, published in Molecular Neurobiology, investigated the effects of needling one acupuncture point on the leg. The research team measured a remarkable effect. Acupuncture point SP6, Sanyinjiao, is depicted in this image. Manual acupuncture stimulation downregulated M1 macrophages (pro-inflammatory cells) and upregulated M2 macrophages (anti-inflammatory cells). As a result, acupuncture reduced pain and swelling.

This neurobiological acupuncture continuing education study solves a great mystery, how does acupuncture work? The secret is in sp6-sanyinjiao-m2the biochemistry. M2 macrophages are an important source of IL-10 (interleukin-10), an anti-inflammatory cytokine that plays an important role in immune responses. Cytokines are proteins released by cells that regulate reactions between cells. Manual acupuncture successfully downregulates M1 macrophages and upregulates M2 macrophages thereby promoting the release of greater IL-10 concentrations. As a result of IL-10 release, pain and inflammation significantly reduce.

This study measured responses in muscle tissues and confirmed that M1 to M2 macrophage phenotype switching is triggered by acupuncture stimulation. Acupuncture literally flips a switch wherein initial inflammatory responses are reduced and the secondary healing responses are promoted. M1 macrophage downregulation and M2 macrophage upregulation triggered by acupuncture was positively associated with reductions in muscle pain and inflammation.

The researchers tested the biochemical process by adding an IL-10 blocking agent in the laboratory experiment. When IL-10 was chemically blocked, acupuncture did not reduce pain and swelling. However, when no blocking agent was applied, acupuncture successfully reduced both pain and swelling. The M2 macrophage upregulation by manual acupuncture successfully created a greater source of IL-10. The researchers note, “These findings provide new evidence that MA (manual acupuncture) produces a phenotypic switch in macrophages and increases IL-10 concentrations in muscle to reduce pain and inflammation.”

Macrophages are required by the body to resolve muscle injury. During injury, M1 macrophages are produced and release inflammatory biochemicals including pro-inflammatory cytokines. M2 macrophages have anti-inflammatory properties and promote the release of interleukin-10. An injury process features an initial inflammatory stage wherein M1 pro-inflammatory macrophages are upregulated. A secondary recovery phase wherein M2 anti-inflammatory macrophages are upregulated helps to promote healing and repair. Manual acupuncture successfully triggered the phenotype switch wherein the M1 macrophages were downregulated and M1 macrophages were upregulated thereby allowing increased IL-10, reductions in pain and decreased swelling.

Acupuncture continuing education in the form of basic research and clinical medicine has helped to measure positive patient outcomes and the biochemical mechanisms by which acupuncture exerts its beneficial medical effects. This latest study helps to unlock one of the greatest secrets of acupuncture, how does it stop pain? Now, scientists can quantifiably measure specific biochemical processes triggered by acupuncture and the resultant positive health outcomes.

 

Getting To The Point
The acupuncture point tested in this investigation was SP6 (Sanyinjiao, Three Yin Intersection). SP6 is located 3 cun directly above the tip of the medial malleolus, on the posterior border of the medial aspect of the tibia. According to Traditional Chinese Medicine (TCM) theory, SP6 strengthens the spleen, transforms dampness, spreads liver qi and benefits the kidneys. SP6 indicated for the treatment of abdominal pain & distention, diarrhea, dysmenorrhea, irregular menstruation, uterine bleeding, leukorrhea, prolapse of the uterus, sterility, difficult or delayed labor, nocturnal emissions, enuresis, dysuria, lower limb atrophy or motor impairment, lower limb hemiplegia, vertigo due to blood deficiency and insomnia. SP6 is the meeting point of the three lower yin meridians: spleen, liver and kidney. A globe and DNA are represented here.

 

About HealthCMi: The Healthcare Medicine Institute (HealthCMi) publishes news and research on acupuncture, herbal medicine and traditional medicine.  HealthCMi provides acupuncture CEU and NCCAOM PDA online courses to licensed acupuncturists for acupuncture continuing education credit.  To submit an article for publication consideration, visit www.healthcmi.com and click on the contact us link.

References:
da Silva, Morgana D., Franciane Bobinski, Karina L. Sato, Sandra J. Kolker, Kathleen A. Sluka, and Adair RS Santos. “IL-10 Cytokine Released from M2 Macrophages Is Crucial for Analgesic and Anti-inflammatory Effects of Acupuncture in a Model of Inflammatory Muscle Pain.” Molecular Neurobiology (2014): 1-13.

Rafael Torres-Rosas, Ghassan Yehia, Geber Peña, Priya Mishra, Maria del Rocio Thompson-Bonilla, Mario Adán Moreno-Eutimio, Lourdes Andrea Arriaga-Pizano, Armando Isibasi, Luis Ulloa. Dopamine mediates vagal modulation of the immune system by electroacupuncture. Nature Medicine, 2014; DOI: 10.1038/nm.3479.

Wang, Ying, Rebekka Gehringer, Shaaban A. Mousa, Dagmar Hackel, Alexander Brack, and Heike L. Rittner. “CXCL10 Controls Inflammatory Pain via Opioid Peptide-Containing Macrophages in Electroacupuncture.” PloS one 9, no. 4 (2014): e94696.
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3 Tips to Easily Alleviate Your Stress Immediately

stress-06092014Stress from day-to-day life can have an extremely negative impact on our health, emotionally, mentally, and physically as well. Long-term or extreme stress can result in frequent or chronic headaches, muscle aches, sleeplessness, anxiety, fatigue, depression, etc. All of these problems only present even more problems to our health and overall well-being. How can we prevent stress from our everyday lives from becoming a much larger problem in our lives?

In the interest of being helpful, I have compiled my favorite 3 tips to easily alleviate your stress, hopefully to the benefit of many individuals suffering from stress-related ailments in their lives. continue reading »

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13 Ways Acupuncture Can Change Your Life

Heal
Heal
Vitality
Vitality

    Posted: 01/03/2013 4:20 pm Sara Calabro SPRING REVITALIZATION!  I am excited to explain how acupuncture works and sharing acupuncture-inspired tips for leading a healthier, simpler, more meaningful life to residents of the Walla Walla Valley, Dayton and surrounding towns. Acupuncture helps us see the world differently — with more hope, openness, intention, gratitude, compassion, patience and clarity. In doing so, it changes us. continue reading »

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Acupuncture Beats Drugs For Shingles Nerve Pain

Acupuncture Beats Drugs For Shingles Nerve Pain

article from HealthCMishingleszostergb34sp10

 

Acupuncture combined with moxibustion was determined more effective than the drug gabapentin for the treatment of shingles, herpes zoster. New research compared the effects of acupuncture followed by local moxibustion against a group that received gabapentin and sham acupuncture. The true acupuncture group had an effective rate of 94% and the drug group had an effective rate of 86%. Acupoints for shingles. Gabapentin (neurontin) is a pharmaceutical medication often used to treat nerve pain, especially in cases nerve pain due to shingles (post-herpetic neuralgia). True acupuncture was applied to Ashi points. Sham acupuncture is a form of simulated acupuncture used to help establish controls in clinical investigations and assists in ruling out the placebo effect. In this study, sham non-acupuncture points were needled in the distal region of the herpetic lesions. This type of sham control has received recent criticism by researchers in that sham needling may provide medical benefits thereby skewing data towards underestimating the healing powers of true acupuncture. Moxibustion involves burning herbs, usually Ai Ye (mugwort), near the skin to provide penetrating warmth. Moxibustion is often combined with acupuncture by licensed acupuncturists in clinical settings. In this study, moxibustion (moxa) was applied for 15 minutes in the region of the lesions. The treatment of shingles has historically been treated by acupuncture within the Traditional Chinese Medicine (TCM) system for well over 1,000 years. This new research confirms the efficacy of acupuncture for the treatment of nerve pain related to the sequela of shingles. The team estimated the cost of care for both groups and determined that acupuncture is both effective and cost-effective for the treatment of nerve pain due to shingles. Doll with acupoints. TCM The historical treatment of shingles with acupuncture often involves, according to TCM principles, the treatment of endogenous damp heat. A Zang-Fu diagnosis may confirm excess liver and gallbladder fire and exogenous toxins. Treatment may involve acupuncture points LI11 (Quchi), SP10 (Xuehai), UB40 (Weizhong), GB34 (Yanglingquan) and LV3 (Taichong). According to TCM principles, this combination of acupuncture points dispels wind, clears heat toxins, clears heat in the blood and clears liver and gallbladder damp heat.

 

Reference: Huang, S. X., M. Mao, J. J. Pu, Y. H. Chen, L. Deng, H. Zhao, M. J. Geng et al. “Clinical research on fire filiform needle combined with mild moxibustion for postherpetic neuralgia.” Zhongguo zhen jiu [Chinese acupuncture & moxibustion] 34, no. 3 (2014): 225. – See more at: http://www.healthcmi.com/Acupuncture-Continuing-Education-News/1314-acupuncture-beats-drugs-for-shingles-nerve-pain#sthash.rHpSfuXa.dpuf

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Lose weight this summer with acupuncture

summer-beach-05272014Blue Valley Acupuncture Clinic-Dayton, WA.-Serving Walla Walla area

 

June Coupon Special in the Waitsburg Times

 

One of the vexing aspects of the approach of summer is how you can obtain your “swimsuit body.” While the winter months, especially around the holidays, are a time for putting on some weight, the summer months are reserved for strenuous activity, especially on the beach. continue reading »

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Auricular Acupuncture Helps With Weight Loss

 

Auricular Acupuncture Weight Loss Found Effective

 

 Blue Valley Acupuncture Clinic- Located in Dayton, Wa. Serving greater Walla Walla area, Waitsburg, Starbuck & Pomeroy.

Article provided by HealthCMI

ear_acupuncture_hunger auricular_acupunctture_hunger

Auricular acupuncture successfully treats obesity. A new study concludes that a special 5 point combination of auricular acupuncture points is effective for weight loss in overweight individuals. Ear acupuncture for the treatment of obesity and hunger is depicted here.
Ear Acupuncture
A one point auricular treatment was also found effective but not to the degree of clinical success as the 5 acupuncture point combination.

A randomised controlled clinical trial of a total of 91 patients with a BMI (body mass index) of 23 or greater were divided into 3 groups. Group 1 received the 5 acupuncture point combination. Group 2 received only one acupuncture point and group 3 received sham acupuncture. At both 4 and 8 weeks following the treatment regime, measurements were taken to determine clinical effectiveness. It was discovered that the 5 acupuncture point combination was the most effective yielding over a 6% reduction in the body mass index. The one point acupuncture treatment regime yielded just under a 6% improvement in BMI. Both groups 1 and 2 showed significant improvements in BMI and weight loss.

Group 1 received 5 auricular acupuncture points: shenmen, spleen, stomach, hunger, endocrine. Group 2 received only one auricular acupuncture point: hunger. Group 3, the sham group, was needled at the 5 auricular acupuncture points but the needles were then immediately removed. The unilateral application of the acupuncture needles was applied once per week. Both groups 1 and group 2 retained a total needle time of 8 weeks using the ear tacks, tiny acupuncture needles attached by tape. Group 3 only received local auricular stimulation of the acupuncture points to simulate the experience but the points were not retained.

A special type of tape retained the needles over the 8 week period for groups 1 and 2. The same tape hid the absence of needles in the sham group. The needle depth was 2 millimeters in the auricular acupuncture points. The 5 point acupuncture treatment caused the most significant reduction in waist circumference and BMI. Body fat percentage dropped significantly in the 5 point acupuncture treatment but not in the other groups.

The 5 auricular acupuncture point combination is commonly employed for digestion issues. Gastric and duodenal ulcers are commonly treated with a similar combination of auricular stomach or duodenum, brain, mouth, spleen and shenmen. The 5 acupuncture point weight loss combination used in the study includes auricular shenmen, located in the triangular fossa at the bifurcating point between the superior and inferior antihelix crus at the lateral 1/3 of the triangular fossa. Auricular acupuncture for weight loss is shown here.
Ear Acupuncture Model

The spleen point has two major auricular locations; one is located on the middle of the back side of the ear. The other location is at the lateral and superior aspect of the cavum concha. The cavum concha point is more commonly applied in clinical settings. The spleen auricular point is traditionally used for strengthening the spleen and harmonizing the stomach. It helps to produce ying-blood and benefits the muscles. Common indications treated with the spleen auricular point are uterine bleeding, abdominal distention, diarrhea and other digestive dysfunctions. The stomach auricular acupuncture point is located at the end of the cruz of the helix in the cavum concha. It is the area formed by the end of the crus of the helix and the border of the lower antehelix cruz.

The endocrine point used in the 5 acupuncture point combination is located in the cavum concha in the intertragic notch. The endocrine point is classically applied within TCM (Traditional Chinese Medicine) for removing liver qi stagnation, regulating the menses, invigorating the blood, expelling wind and benefitting the lower jiao. Indications for use of this auricular point include skin disorders, impotence, irregular menstruation and endocrine system dysfunction.

The hunger auricular acupuncture point is located on the lower part of the tragus in the direction of the transitional fold near the facial skin. The hunger point can be used to up-regulate or down-regulate sensations of hunger. It is used for issues of anorexia, bulimia and digestive disturbances.

Reference:
S. Yeo, K. S. Kim, S. Lim. Randomised clinical trial of five ear acupuncture points for the treatment of overweight people. Acupuncture in Medicine, 2013; DOI: 10.1136/acupmed-2013-010435.

– See more at: http://www.healthcmi.com/Acupuncture-Continuing-Education-News/1218-auricular-acupuncture-weight-loss-found-effective?highlight=WyJ3ZWlnaHQiLCJsb3NzIiwid2VpZ2h0IGxvc3MiXQ==#sthash.kmghw5kZ.dpuf

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Untitled

 

Researchers have discovered how to measure and validate the existence of acupuncture points and their meridians. MRI studies and oxygen sensor studies come from some of the most prestigious universities in the world. Today, I want to start with remarkable research from investigators at one of the most prestigious universities in Korea.

Sungkyunkwan University (Seoul) was founded in 1398. Yes, over 600 years ago! It was recently acquired by the Samsung Group in 1996, which has helped preserve its legacy of excellence with substantial financial support. The university is a leader in many fields including nanotechnology and natural sciences, features a dual degree program with Ohio State University and has a collaborative program with the MIT (Massachusetts Institute of Technology) Sloan School of Management.

Two researchers from Sungkunkwan Univeristy worked with another researcher from the Department of Chemistry and Nano Science at Ewha Womans University on this ground breaking research. Notably, Ewha Womans University is considered one of the most prestigious schools in Korea and produced Korea’s first female doctor, lawyer, justice on the Constitutional Court and the first female prime minister of Korea.

Why all the fuss about researchers and the schools they hail from? In the many years I have worked in Chinese and Oriental Medicine, I have uniformly come across skepticism and resistance to valuable, peer reviewed research. I want to give a little background before going forward with something as important as this research. For some it seems, no research institute or study is sufficient so long as it says something positive about acupuncture and herbal medicine. Ethnocentrism abound, I wanted to stave off imperious pans decrying putative proofs and to assuage presumptive skepticism and concomitant guetapens. Perhaps establishing the authenticity and seriousness of the institutions from which the research emanates helps equanimity to mollify incredulity and for rapprochement to exist between the skeptic and modern scientists whose works demonstrate the existence of acupuncture points and their functions.

The research from Sungkyunkwan University and Ewha Woman University is entitled Heterogeneity of Skin Surface Oxygen Level of Wrist in Relation to Acupuncture Point.[1] The study used an amperometric oxygen microsensor to detect partial oxygen pressure variations at different locations on the anterior aspect of the left wrist. The researchers concluded that partial oxygen pressure is significantly higher at acupuncture points.

Below are two images from the study measuring the increase of partial oxygen pressure combined with an overlay of the local acupuncture point locations. The images are representative of typical readings found in the study and remarkably map the Lung Hand Taiyin, Pericardium Hand Jueyin and Heart Shaoyin channels and their associated local points. Depicted are P7 and P6 clearly showing high oxygen pressure levels. The same is true for LU9, LU8, HT7, HT6, HT5 and HT4. Note that non-acupuncture point regions do not show higher oxygen pressure levels. These measurements are not needled points but are natural resting states of acupuncture points absent stimulation. This biomedical research gives us insight into the structural makeup of acupuncture points. This type of basic research is not isolated and numerous studies from multitudes of the top research centers and universities demonstrate specific properties and physiological actions of acupuncture points.

Wrist acupuncture points including the Peridcardium channel and Lung channel.
Oxygen Pressure at Acupuncture Points

wrist1

 

Wrist acupuncture points another image.
Another Acupuncture Oxygen Pressure Sample

– See more at: http://www.healthcmi.com/Acupuncture-Blog/758-acupointgb40#sthash.RUU7LZZz.dpuf

 

The nexus of most research on the physical existence of acupuncture points and acupuncture meridians is hemodynamic, MRI, oxygen pressure, histological, physiological, clinical and electroconductivity research. Researchers at the University of California School of Medicine (Irvine, California) noted, “Recent evidence shows that stimulation of different points on the body causes distinct responses in hemodynamic, fMRI and central neural electrophysiological responses.” The investigators reviewed MRI results and noted that “stimulation of different sets of acupoints leads to disease-specific neuronal responses, even when acupoints are located within the same spinal segment.” This summarizes research in the vanguard of technical documentation on acupuncture.[2][3]

University of California researchers Choi, Jiang and Longhurst note of acupuncture, “hemodynamic, functional magnetic resonance imaging and neurophysiological studies evaluating the responses to stimulation of multiple points on the body surface have shown that point-specific actions are present.”[4] Naturally, they are running into the difficulty of AhShi points and their specific actions. Perhaps they will discover new effective actions for AhShi points as a result of basic research. Other research shows point specificity in brain physiology and reflects the overall direction of scientific investigation in the field of acupuncture.

 

 

 

 

 

 

 

 

 

 

wrist2

The Journal of Magnetic Resonance Imaging featured research on the neurophysiological effects of acupuncture points using MRI imaging noting that acupoint GB40 stimulation enhanced “connectivity between the superior temporal gyrus (STG) and anterior insula.” The investigators concluded, “The current study demonstrates that acupuncture at different acupoints could exert different modulatory effects on RSNs. Our findings may help to understand the neurophysiological mechanisms underlying acupuncture specificity.”[5] Here, the researchers have validated acupuncture point specificity and suggest a possible physiological model of understanding acupuncture points.

HRV (Heart Rate Variability) is a measure of cardiovascular health. One study notes that, “HRV changes significantly during auricular acupuncture….” This research also notes that, “HRV total increases during auricular acupuncture….”[6] Another related study from the International Society for Autonomic Neuroscience notes that acupuncture “causes the modulation of cardiac autonomic function.” These are but two examples of investigations citing specific medicinal actions of specific acupuncture points and is in no way exhaustive of the vast body of research demonstrating acupuncture point specificity for the treatment of hypertension, atrial fibrillation and other cardiovascular disorders.[7] Investigators from the University of California (Los Angeles and Irvine) “have shown that electroacupuncture stimulation activates neurons” in specific brain regions thereby reducing hypertension.[8]

Dr. Berman, M.D. served as a lead researcher in a University of Maryland School of Medicine investigation published in the prestigious Annals of Internal Medicine. The research concludes that, “Acupuncture seems to provide improvement in function and pain relief as an adjunctive therapy for osteoarthritis of the knee when compared with credible sham acupuncture and education control groups.”[9] What is interesting in this clinical trial is that it was an early study showing that sham acupuncture was not as effective as verum acupuncture. The study sought to isolate and address the placebo effect and found that it is not responsible for the medical benefits associated with acupuncture therapy. There are many papers showing the specific medical benefits of acupuncture on internal organs, tissues and towards the resolution of specific ailments. I thought I would highlight this investigation given its historical value.

Einstein’s Theory of Relativity initially did not catch on and was ridiculed before acceptance. The same is true for much of medicine both old and new. People’s presuppositions often circumvent equanimity and receptiveness to new insights. Backing up a bit, one might have thought that a basic neurologic test for the Babinski Sign was pure fiction. It may have seemed logical and self-evident that rubbing someone’s foot and looking for dorsiflexion of the great toe and fanning of the other toes could not possibly indicate brain or spinal cord damage. Yet, the great French neurologist of Polish origin, Babinski, discovered that this plantar reflex identifies central nervous system damage, which is now an accepted medical reality by medical doctors and is an effective diagnostic tool for central nervous system damage.

Acupuncturists and herbalists have faced acrimonious traducements and caluminiations towards substantiated supportive research. Often there is a predilection towards rejecting the efficacy of Chinese and Oriental Medicine that trumps the realities of hard evidence and smacks of ethnocentrism. The Flat Earth Society felt the same way about the infidels suggesting that the earth is round. Galileo had his fair share of troubles too. It cannot be underestimated how high the stakes really are for patient care and beneficial patient outcomes. At risk is non-integration of cost-effective medicine that roots out the source of suffering by healing illness. A time honored traditional clinical medicine history combined with supportive modern research data suggests that acupuncture is an effective modality of therapeutic care. Acupuncture seems impossible? Recall the words of Mark Twain, “Fiction is obliged to stick to possibilities. Truth isn’t.”

It may appear to some that it is self-evident and logical that acupuncture points exist only as part of some sort of chimerical hermeneutic system. However, extensive research has already been conducted at major universities worldwide demonstrating not only that acupuncture points and meridians exist but also how they physiologically function. There is a resistance to an enormous body of research. Cloaked in veil of mature skepticism and realism, naysayers grasp at piecemeal attack pieces to fight off what has already been measured, documented and peer reviewed both in individual studies and large scale meta-analyses. I suggest an era of open-mindedness towards the modern research documenting the efficacy of Chinese and Oriental medicine, acupuncture and herbal medicine.

Footnotes:
[1] Minyoung Hong, Sarah S. Park, Yejin Ha, et al., “Heterogeneity of Skin Surface Oxygen Level of Wrist in Relation to Acupuncture Point,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 106762, 7 pages, 2012. doi:10.1155/2012/10a6762.
[2] Point specificity in acupuncture. Chin Med. 2012 Feb 28;7:4. doi: 10.1186/1749-8546-7-4. Choi EM, Jiang F, Longhurst JC.
[3] Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine CA 92697-4075, USA.
[4] Point specificity in acupuncture. Chin Med. 2012 Feb 28;7:4. doi: 10.1186/1749-8546-7-4. Choi EM, Jiang F, Longhurst JC.
[5] Zhong, C., Bai, L., Dai, R., Xue, T., Wang, H., Feng, Y., Liu, Z., You, Y., Chen, S. and Tian, J. (2011), Modulatory effects of acupuncture on resting-state networks: A functional MRI study combining independent component analysis and multivariate granger causality analysis. Journal of Magnetic Resonance Imaging.
[6] Evidence-Based Complementary and Alternative Medicine. Volume 2012 (2012), Article ID 817378, 7 pages. doi:10.1155/2012/817378. Sino-European Transcontinental Basic and Clinical High-Tech Acupuncture Studies—Part 1: Auricular Acupuncture Increases Heart Rate Variability in Anesthetized Rats. Xin-Yan Gao, Kun Liu, Bing Zhu and Gerhard Litscher.
[7] Kurono Y, Minagawa M, Ishigami T, Yamada A, Kakamu T, Hayano J. Auton Neurosci. Acupuncture to Danzhong but not to Zhongting increases the cardiac vagal component of heart rate variability. 2011 Apr 26;161(1-2):116-20. Epub 2011 Jan 7.
[8] Evidence-Based Complementary and Alternative Medicine. Volume 2012 (2012), Article ID 878673, 9 pages. doi:10.1155/2012/878673. Neuroendocrine Mechanisms of Acupuncture in the Treatment of Hypertension. Wei Zhou and John C. Longhurst. Department of Anesthesiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA. Department of Medicine, University of California Irvine, Irvine, CA.
[9] Ann Intern Med, Berman, Lixing, Lagenberg, Lee, Gilpin, Hochberg. 2004; 141:901-910.
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Pictures of Acupuncture Points Along Meridians

The Existence of Acupuncture Pointscartoonwebpost

22 MAY 2013.

Artitcle compliments of HealthCMI

 

Researchers have discovered how to measure and validate the existence of acupuncture points and their meridians. MRI studies and oxygen sensor studies come from some of the most prestigious universities in the world. Today, I want to start with remarkable research from investigators at one of the most prestigious universities in Korea.

Sungkyunkwan University (Seoul) was founded in 1398. Yes, over 600 years ago! It was recently acquired by the Samsung Group in 1996, which has helped preserve its legacy of excellence with substantial financial support. The university is a leader in many fields including nanotechnology and natural sciences, features a dual degree program with Ohio State University and has a collaborative program with the MIT (Massachusetts Institute of Technology) Sloan School of Management.

Two researchers from Sungkunkwan Univeristy worked with another researcher from the Department of Chemistry and Nano Science at Ewha Womans University on this ground breaking research. Notably, Ewha Womans University is considered one of the most prestigious schools in Korea and produced Korea’s first female doctor, lawyer, justice on the Constitutional Court and the first female prime minister of Korea.

Why all the fuss about researchers and the schools they hail from? In the many years I have worked in Chinese and Oriental Medicine, I have uniformly come across skepticism and resistance to valuable, peer reviewed research. I want to give a little background before going forward with something as important as this research. For some it seems, no research institute or study is sufficient so long as it says something positive about acupuncture and herbal medicine. Ethnocentrism abound, I wanted to stave off imperious pans decrying putative proofs and to assuage presumptive skepticism and concomitant guetapens. Perhaps establishing the authenticity and seriousness of the institutions from which the research emanates helps equanimity to mollify incredulity and for rapprochement to exist between the skeptic and modern scientists whose works demonstrate the existence of acupuncture points and their functions.

The research from Sungkyunkwan University and Ewha Woman University is entitled Heterogeneity of Skin Surface Oxygen Level of Wrist in Relation to Acupuncture Point.[1] The study used an amperometric oxygen microsensor to detect partial oxygen pressure variations at different locations on the anterior aspect of the left wrist. The researchers concluded that partial oxygen pressure is significantly higher at acupuncture points.

Below are two images from the study measuring the increase of partial oxygen pressure combined with an overlay of the local acupuncture point locations. The images are representative of typical readings found in the study and remarkably map the Lung Hand Taiyin, Pericardium Hand Jueyin and Heart Shaoyin channels and their associated local points. Depicted are P7 and P6 clearly showing high oxygen pressure levels. The same is true for LU9, LU8, HT7, HT6, HT5 and HT4. Note that non-acupuncture point regions do not show higher oxygen pressure levels. These measurements are not needled points but are natural resting states of acupuncture points absent stimulation. This biomedical research gives us insight into the structural makeup of acupuncture points. This type of basic research is not isolated and numerous studies from multitudes of the top research centers and universities demonstrate specific properties and physiological actions of acupuncture points.

– See more at: http://www.healthcmi.com/Acupuncture-Blog/758-acupointgb40#sthash.RUU7LZZz.dpuf

wrist2
Oxygen Pressure at Acupuncture Points

 

 

 

 

 

 

 

 

The nexus of most research on the physical existence of acupuncture points and acupuncture meridians is hemodynamic, MRI, oxygen pressure, histological, physiological, clinical and electroconductivity research. Researchers at the University of California School of Medicine (Irvine, California) noted, “Recent evidence shows that stimulation of different points on the body causes distinct responses in hemodynamic, fMRI and central neural electrophysiological responses.” The investigators reviewed MRI results and noted that “stimulation of different sets of acupoints leads to disease-specific neuronal responses, even when acupoints are located within the same spinal segment.” This summarizes research in the vanguard of technical documentation on acupuncture.[2][3]

University of California researchers Choi, Jiang and Longhurst note of acupuncture, “hemodynamic, functional magnetic resonance imaging and neurophysiological studies evaluating the responses to stimulation of multiple points on the body surface have shown that point-specific actions are present.”[4] Naturally, they are running into the difficulty of AhShi points and their specific actions. Perhaps they will discover new effective actions for AhShi points as a result of basic research. Other research shows point specificity in brain physiology and reflects the overall direction of scientific investigation in the field of acupuncture.

The Journal of Magnetic Resonance Imaging featured research on the neurophysiological effects of acupuncture points using MRI imaging noting that acupoint GB40 stimulation enhanced “connectivity between the superior temporal gyrus (STG) and anterior insula.” The investigators concluded, “The current study demonstrates that acupuncture at different acupoints could exert different modulatory effects on RSNs. Our findings may help to understand the neurophysiological mechanisms underlying acupuncture specificity.”[5] Here, the researchers have validated acupuncture point specificity and suggest a possible physiological model of understanding acupuncture points.

HRV (Heart Rate Variability) is a measure of cardiovascular health. One study notes that, “HRV changes significantly during auricular acupuncture….” This research also notes that, “HRV total increases during auricular acupuncture….”[6] Another related study from the International Society for Autonomic Neuroscience notes that acupuncture “causes the modulation of cardiac autonomic function.” These are but two examples of investigations citing specific medicinal actions of specific acupuncture points and is in no way exhaustive of the vast body of research demonstrating acupuncture point specificity for the treatment of hypertension, atrial fibrillation and other cardiovascular disorders.[7] Investigators from the University of California (Los Angeles and Irvine) “have shown that electroacupuncture stimulation activates neurons” in specific brain regions thereby reducing hypertension.[8]

wrist1
Oxygen Pressure at Acupuncture Points

Dr. Berman, M.D. served as a lead researcher in a University of Maryland School of Medicine investigation published in the prestigious Annals of Internal Medicine. The research concludes that, “Acupuncture seems to provide improvement in function and pain relief as an adjunctive therapy for osteoarthritis of the knee when compared with credible sham acupuncture and education control groups.”[9] What is interesting in this clinical trial is that it was an early study showing that sham acupuncture was not as effective as verum acupuncture. The study sought to isolate and address the placebo effect and found that it is not responsible for the medical benefits associated with acupuncture therapy. There are many papers showing the specific medical benefits of acupuncture on internal organs, tissues and towards the resolution of specific ailments. I thought I would highlight this investigation given its historical value.

Einstein’s Theory of Relativity initially did not catch on and was ridiculed before acceptance. The same is true for much of medicine both old and new. People’s presuppositions often circumvent equanimity and receptiveness to new insights. Backing up a bit, one might have thought that a basic neurologic test for the Babinski Sign was pure fiction. It may have seemed logical and self-evident that rubbing someone’s foot and looking for dorsiflexion of the great toe and fanning of the other toes could not possibly indicate brain or spinal cord damage. Yet, the great French neurologist of Polish origin, Babinski, discovered that this plantar reflex identifies central nervous system damage, which is now an accepted medical reality by medical doctors and is an effective diagnostic tool for central nervous system damage.

Acupuncturists and herbalists have faced acrimonious traducements and caluminiations towards substantiated supportive research. Often there is a predilection towards rejecting the efficacy of Chinese and Oriental Medicine that trumps the realities of hard evidence and smacks of ethnocentrism. The Flat Earth Society felt the same way about the infidels suggesting that the earth is round. Galileo had his fair share of troubles too. It cannot be underestimated how high the stakes really are for patient care and beneficial patient outcomes. At risk is non-integration of cost-effective medicine that roots out the source of suffering by healing illness. A time honored traditional clinical medicine history combined with supportive modern research data suggests that acupuncture is an effective modality of therapeutic care. Acupuncture seems impossible? Recall the words of Mark Twain, “Fiction is obliged to stick to possibilities. Truth isn’t.”

It may appear to some that it is self-evident and logical that acupuncture points exist only as part of some sort of chimerical hermeneutic system. However, extensive research has already been conducted at major universities worldwide demonstrating not only that acupuncture points and meridians exist but also how they physiologically function. There is a resistance to an enormous body of research. Cloaked in veil of mature skepticism and realism, naysayers grasp at piecemeal attack pieces to fight off what has already been measured, documented and peer reviewed both in individual studies and large scale meta-analyses. I suggest an era of open-mindedness towards the modern research documenting the efficacy of Chinese and Oriental medicine, acupuncture and herbal medicine.

Footnotes:
[1] Minyoung Hong, Sarah S. Park, Yejin Ha, et al., “Heterogeneity of Skin Surface Oxygen Level of Wrist in Relation to Acupuncture Point,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 106762, 7 pages, 2012. doi:10.1155/2012/10a6762.
[2] Point specificity in acupuncture. Chin Med. 2012 Feb 28;7:4. doi: 10.1186/1749-8546-7-4. Choi EM, Jiang F, Longhurst JC.
[3] Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine CA 92697-4075, USA.
[4] Point specificity in acupuncture. Chin Med. 2012 Feb 28;7:4. doi: 10.1186/1749-8546-7-4. Choi EM, Jiang F, Longhurst JC.
[5] Zhong, C., Bai, L., Dai, R., Xue, T., Wang, H., Feng, Y., Liu, Z., You, Y., Chen, S. and Tian, J. (2011), Modulatory effects of acupuncture on resting-state networks: A functional MRI study combining independent component analysis and multivariate granger causality analysis. Journal of Magnetic Resonance Imaging.
[6] Evidence-Based Complementary and Alternative Medicine. Volume 2012 (2012), Article ID 817378, 7 pages. doi:10.1155/2012/817378. Sino-European Transcontinental Basic and Clinical High-Tech Acupuncture Studies—Part 1: Auricular Acupuncture Increases Heart Rate Variability in Anesthetized Rats. Xin-Yan Gao, Kun Liu, Bing Zhu and Gerhard Litscher.
[7] Kurono Y, Minagawa M, Ishigami T, Yamada A, Kakamu T, Hayano J. Auton Neurosci. Acupuncture to Danzhong but not to Zhongting increases the cardiac vagal component of heart rate variability. 2011 Apr 26;161(1-2):116-20. Epub 2011 Jan 7.
[8] Evidence-Based Complementary and Alternative Medicine. Volume 2012 (2012), Article ID 878673, 9 pages. doi:10.1155/2012/878673. Neuroendocrine Mechanisms of Acupuncture in the Treatment of Hypertension. Wei Zhou and John C. Longhurst. Department of Anesthesiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA. Department of Medicine, University of California Irvine, Irvine, CA.
[9] Ann Intern Med, Berman, Lixing, Lagenberg, Lee, Gilpin, Hochberg. 2004; 141:901-910.
– See more at: http://www.healthcmi.com/Acupuncture-Blog/758-acupointgb40#sthash.RUU7LZZz.dpuf

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Turmeric: A Chinese Herbal Perspective

 

Blue Valley Acupuncture Clinic

Located in Dayton, WA.-Serving greater Walla Walla area & nearby towns of Waitsburg, Starbuck & Pomeroy

Turmeric: Pros, Cons, and Contraindications

turmeric

Written by Lesley Tierra

 

Turmeric has become increasingly popular over the last decade, first for blood purification and then for joint pain. As it’s hit the mainstream, its uses have narrowed at the same time. While turmeric is a fabulous herb with many beneficial applications, it’s also quite powerful and can strongly imbalance the body if over-used or misused. Most people aren’t aware of this and definitely should be.

First, the good news. While both turmeric tuber and rhizome are considered medicinal, the rhizome specifically is both the spice used in Indian cooking and western herbalism. It has a warm energy with a spicy and bitter taste and enters the Spleen, Stomach and Liver. It invigorates the Blood and Qi and has analgesic, emmenagogue, cholagogue, antibacterial, antifungal and anti-inflammatory properties.

Turmeric rhizome treats amenorrhea, dysmenorrhea, sports injuries, trauma pain and swelling, flank, gastric or abdominal congestion and pain, and eases painful obstruction due to Wind, Cold and Damp with Stagnant Blood, particularly in the shoulders. It’s also used for gallstones, hepatitis, wounds, bruises, toothache, hemorrhage, arthritis and cataracts. Further, the rhizome is anti-inflammatory, antioxidant and purifies the blood and liver. It also strengthens digestion, improves intestinal flora, aids in digestion of protein, and treats gas, colic and jaundice.

With all these great uses, what could be harmful about turmeric? Well, now for the bad news. Turmeric is very bitter and so strongly dries the Blood and Yin. If taken for extended periods or overdosed, it can cause dizziness, blurry vision, insomnia, dry eyes, burning in the hands and feet, steaming bone disorder and night sweats.

I have had many a patient come in with such symptoms, uncertain as to what may have caused them. Because they didn’t have a typical Yin Deficient constitution, we investigated further and found high doses of turmeric supplements often the culprit.

Because it is so highly touted in the western marketplace for pain relief, people tend to take tons of turmeric. It’s not unusual for people to take supplements indiscriminately. If such and so is good for this or that, then people automatically take it and for extended periods of time. As well, they think if some is good or helpful, then more is better. And then they continue to take it preventatively when it may no longer be necessary. While either of these approaches is fine for many supplements, for turmeric it is not.

Turmeric does indeed reduce pain and swelling, but overdosing with it or taking it for prolonged periods does deplete the Blood and Yin. This is even more true for vegetarians, vegans and women during menses and so these folks should be particularly careful with this herb. It takes a long time to nourish Yin again, and the dampening herbs that do so put the digestive system at risk.

When recommending any herbs and supplements, first consider a person’s constitution along with all their signs and symptoms before making your choices. Further, it’s best to not use most herbs for a single commercial use. This may cause subsequent negative impact on other aspects of the body, which in turn, can give a bad reputation to that herb because it now has dangerous “side effects.”

Most herbs are mild in nature and don’t have side effects, just improper use. Narrowing an herb’s use to one famous commercial application not only loses the knowledge of the herb’s other effects and can harm people, but also endangers herbalism for us all. Let’s keep our traditional knowledge of herbs alive and use them within the context of the whole person’s needs and not just support its one commercial use. This not only benefits people, but also supports herbal medicine for us all.

 

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Mental Well-being and Acupuncture

 

Denise Lane Acupuncture

Blue Valley Acupuncture Clinic-Located in Dayton, WA.-serving greater Walla Walla area & nearby towns.

 

Mental Well-being and Acupuncture

 

yintang-powerful calming point

Article attributed to HealthCMI
One of the most rewarding aspects of being a licensed acupuncturist is to deliver fast clinical results that directly improves the life of the patient. Acupuncture for the treatment of panic attacks is one of the more dramatic treatment protocols because of the immediate impact it has on patients’ lives. Often, from the time of the very first acupuncture treatment, the patient has a decrease in the frequency, intensity and duration of panic attacks. As the process continues, patients gain a greater sense of well-being, centeredness, self-confidence and control over their lives.

I remember treating a Vietnam veteran about ten years ago. Decades after his extreme combat experiences, he had never slept more than two complete hours consecutively. The stress, exhaustion and mental restlessness had withered this man to a shell of what he once was. Psychologically, he had made peace wit his past. Physiologically, however, his body and brain chemistry had suffered from post traumatic stress syndrome (PTSD) and he was unable to fully recover from the impact of his experiences.

After the first acupuncture treatment he was able to sleep up to about four hours per night. After a few weeks of acupuncture, his sleep pattern normalized. He no longer experienced panic attacks and no longer woke up covered in sweat from nightmares. He came in to my office for routine checkups until he felt fully recovered. It was incredible to see his face change. The stress fell from his eyes and cheeks. His complexion returned. His wooden exterior softened into that of a happy man. Eventually, he fell in love and got married.

Most panic attack patients at my clinic tend to be hard working individuals with very busy schedules. Everyday stresses in the workplace combined with family and relationship struggles tend to build up in the system until the psyche breaks. Combine some of the aforementioned issues with lack of time for reflection and rest, financial struggles and maybe a lack of community support and the average person may see the emergence of panic attacks. Here, Liver Qi Stagnation has the opportunity to turn into Liver Fire. It may also create a cycle of Liver Qi depression with either Yang Uprising or excess Fire. Naturally, the Heart Shen is poorly nourished as the Liver Yin is depleted. The Qi, Blood, Yin and Yang may be depleted and the consequent stagnation and lack of Yin essence may also create excess Fire. In some cases, Heat in the Blood may develop along with its associated bleeding disorders. Abnormal uterine bleeding and sensory organ disorders are not uncommon in these circumstances.

It’s amazing what a simple release can do for one’s spirit. In some instances, acupuncture is akin to releasing pressurized steam from a tea kettle. Patients with extremely high stress loads may spurt a high pressure mist of blood that emanates from Yin Tang when the needle is removed. It reminds me of an aerosol spray. I usually let my patients know they can expect significant clinical results and a good night’s sleep if I see this release, especially when combined with a release of blood from ear Shenmen when the needle is removed. Naturally, an acupuncturist can analyse the color of the blood released from ear Shenmen to make a more detailed diagnosis.

Common body acupuncture points for the treatment of panic attacks are P7, P6, TB5, HT7, LI11, Sishencong, Yintang, LR3, DU20 and ST44. Nourishing points for patients with panic attacks often include ST36, SP6, K3, and K7. Auricular points vary dependent upon the system used, however, ear Liver, Kidney, Heart, Brain, Sympathetic and Shenmen are common amoung the standard auricular points. In patients prone to depression, using DU24 with a triple side-by-side technique combined with the Chouqi technique simultaneouly on all three points helps to direct the healthy energy upwards while releasing stagnation from the mind and Shen. In all, an acupuncturist simply needs to stick with a classical differential diagnosis to ensure that the upward and descending movement Qi becomes balanced. Some will need strong tonification while many will need better invigoration and circulation of Qi and Blood.

Heavy sedation acupuncture points are often necessary in acute cases wherein the patient may have difficulty in maintaining sanity or composure. This is more common in patients with schizophrenia. Often, acupuncture can reduce a multitude of voices inside the head of the patient to a singular identity during the treatment. I can’t help but have compassion for these individuals. They often feel like they are living in a crowded room of voices and cannot discern their own. Although acupuncture brings significant and immediate results, the acupuncture is useless without tremendous family or community support. For patients suffering from schizophrenia, regularity and discipline are difficult. They fall from their medication regimes and acupuncture treatment schedules. They often engage in behaviors such as staying out late and losing sleep combined with a poor diet. It’s a big job to help these people. Resolving panic attacks for the average patient is straightforward and rapid, however, for patients with schizophrenia this process may be ineffective due to lack of follow through on the patient’s behalf.

Patients suffering from depression and diabetes are another challenge. In both cases, they will respond more slowly to treatment for most disorders. If a patient suffers from both disorders simultaneously, it presents significant clinical challenges. Results will probably come about more slowly. Also, significant attention must be devoted to restoring the patient’s insulin-glucagon pathway. Mental instability due to blood glucose level fluctuations exacerbates the recovery process. Even so, patients with depression and diabetes will usually see resolution of their panic attacks in a timely fashion with the disciplined application of acupuncture care.

– See more at: http://www.healthcmi.com/Acupuncture-Blog/723-panicattacksshenmen#sthash.iLatrww9.dpuf

 

 

Denise Lane Acupuncture

 

 

 

 

 

 

 

 

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